Yongqi Zhen

A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma

Zhiqiang Yao, Xin Zhang, Yongqi Zhen et al. · Cell Death and Disease · 2018 · 107 citations · Full text

Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer

Yongqi Zhen, Rongyan Zhao, Minjuan Wang et al. · Theranostics · 2020 · 74 citations · Full text

Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer

Yongqi Zhen, Zhaoxin Yuan, Jiahui Zhang et al. · Cell Death and Disease · 2022 · 51 citations · Full text

Ferulin C triggers potent PAK1 and p21-mediated anti-tumor effects in breast cancer by inhibiting Tubulin polymerization in vitro and in vivo

Dahong Yao, Dabo Pan, Yongqi Zhen et al. · Pharmacological Research · 2019 · 44 citations

Breast Oncology, Oncology, P21-mediated Anti-tumor Effects +10

Discovery of a Novel Dual-Target Inhibitor of ERK1 and ERK5 That Induces Regulated Cell Death to Overcome Compensatory Mechanism in Specific Tumor Types

Guan Wang, Yuqian Zhao, Yao Liu et al. · Journal of Medicinal Chemistry · 2020 · 40 citations