Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer

Yongqi Zhen, Rongyan Zhao, Minjuan Wang, Xing Jiang, Feng Gao, Leilei Fu, Lan Zhang, Xian‐Li Zhou

Theranostics · 2020 · 75 citations · 44 references

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Abstract

Our results provide novel insights towards the putative anti-cancer efficacy of flubendazole. Furthermore, here we show that flubendazole could serve as a potential therapeutic drug in TNBC. Altogether, this study highlights the possibility of this repurposed autophagic inducer for future cancer treatments.

References

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