Steve Lu

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Dung T. Le, Jennifer N. Durham, Kellie N. Smith et al. · Science · 2017 · 6.6K citations

Life Sciences, Immunology, Oncology +17

Comparison of Biomarker Modalities for Predicting Response to PD-1/PD-L1 Checkpoint Blockade

Steve Lu, Julie E. Stein, David L. Rimm et al. · JAMA Oncology · 2019 · 622 citations · Full text

Medicine, Oncology, Pathology +17

DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

Changzheng Lu, Junhong Guan, Steve Lu et al. · Cancer Cell · 2020 · 276 citations · Full text

Life Sciences, Cancer Biology, Oncology +14

The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer

Austin K. Mattox, Christopher Douville, Yuxuan Wang et al. · Cancer Discovery · 2023 · 178 citations · Full text

Medicine, Cancer Biology, Oncology +12

Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade

Andrew Georgiadis, Jennifer N. Durham, Laurel A. Keefer et al. · Clinical Cancer Research · 2019 · 153 citations · Full text

Medicine, Molecular Genetics, Oncology +17