Changzheng Lu

DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

Changzheng Lu, Junhong Guan, Steve Lu et al. · Cancer Cell · 2020 · 276 citations · Full text

Life Sciences, Cancer Biology, Oncology +14

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

Junhong Guan, Changzheng Lu, Qihuang Jin et al. · Cancer Cell · 2020 · 235 citations · Full text

Life Sciences, Genetics, Molecular Biology +8

Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling

Chuanhui Han, Zhida Liu, Yunjia Zhang et al. · Nature Immunology · 2020 · 144 citations

Medicine, Cancer Biology, Immunology +14

eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer

Shruthy Suresh, Beibei Chen, Jingfei Zhu et al. · Nature Cancer · 2020 · 130 citations · Full text

Life Sciences, Molecular Biology, Oncology +12

Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load

Hao‐Dong Li, Ileana Cuevas, Musi Zhang et al. · Journal of Clinical Investigation · 2018 · 81 citations · Full text

Life Sciences, Genetics, Oncology +16