Hu Yuan

Discovery of Potent Small-Molecule Inhibitors of Ubiquitin-Conjugating Enzyme UbcH5c from α-Santonin Derivatives

Hao Chen, Guozhen Wu, Shuang Gao et al. · Journal of Medicinal Chemistry · 2017 · 51 citations · Full text

Positive Compound 1, Drug Target, Chemoprevention Strategy +26

Structure-based design of glycyrrhetinic acid derivatives as potent anti-sepsis agents targeting high-mobility group box-1

Yuanyuan Wang, Zongmin Yu, Hu Yuan et al. · Bioorganic Chemistry · 2020 · 17 citations

Pharmaceutical Science, Glycyrrhetinic Acid Derivatives, Pharmacology +9

Synthesis and structure–activity relationships of guaiane-type sesquiterpene lactone derivatives with respect to inhibiting NO production in lipopolysaccharide-induced RAW 264.7 macrophages

Hao Chen, Bingyang Chen, Chun‐Ting Liu et al. · European Journal of Medicinal Chemistry · 2014 · 16 citations

Medicinal Chemistry, Biosynthesis, Biochemistry +9

Synthesis of Pyrimidopyrrolopyridazines via a Tandem Reaction of Heterocyclic Ketene Aminals with 1,2-Diaza-1,3-dienes

Menghao Zhao, Xia Li, Jiaan Shao et al. · Organic Letters · 2018 · 16 citations

Synthesis and evaluation of new α-methylene-γ-lactone carbamates with NO production inhibitory effects in lipopolysaccharide-induced RAW 264.7 macrophages

Wen‐Hao Shao, Bingyang Chen, Xiang‐Rong Cheng et al. · European Journal of Medicinal Chemistry · 2015 · 10 citations

Lipid Preparation, Biochemistry, New α-Methylene-γ-lactone Carbamates +4