Sake van Wageningen

Large-Scale Genetic Perturbations Reveal Regulatory Networks and an Abundance of Gene-Specific Repressors

Patrick Kemmeren, Katrin Sameith, Loes A. L. van de Pasch et al. · Cell · 2014 · 304 citations · Full text

Systems Biology, Functional Genomics, Engineering +12

Functional Organization of the S. cerevisiae Phosphorylation Network

Dorothea Fiedler, Hannes Braberg, Monika Mehta et al. · Cell · 2009 · 263 citations · Full text

Signal Transduction, Functional Organization, Natural Sciences +6

Functional Overlap and Regulatory Links Shape Genetic Interactions between Signaling Pathways

Sake van Wageningen, Patrick Kemmeren, Philip Lijnzaad et al. · Cell · 2010 · 133 citations · Full text

Signal Transduction, Functional Genomics, Genetics +13

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models

Xue Zheng, Daniël J. Vis, Alejandra Bruna et al. · Cell Research · 2018 · 128 citations · Full text

ID1 and ID2 are retinoic acid responsive genes and induce a G0/G1 accumulation in acute promyelocytic leukemia cells

Jeannet Nigten, Marleen C. Breems-de Ridder, Claudia Erpelinck-Verschueren et al. · Leukemia · 2005 · 49 citations

Hematological Malignancy, Cell Regulation, Mixed-phenotype Acute Leukemia +7