Alejandra Bruna

Progesterone receptor modulates ERα action in breast cancer

Hisham Mohammed, I. Alasdair Russell, Rory Stark et al. · Nature · 2015 · 644 citations

Breast Oncology, Hormonal Receptor, Gynecology +4

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

Peter Eirew, Adi Steif, Jaswinder Khattra et al. · Nature · 2014 · 630 citations · Full text

Xenotransplantation, Somatic Variant, Tumor Heterogeneity +12

High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene

Alejandra Bruna, Rachel S. Darken, Federico Rojo et al. · Cancer Cell · 2007 · 473 citations · Full text

Tumor Biology, Glioma, Medicine +11

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

Alejandra Bruna, Oscar M. Rueda, Wendy Greenwood et al. · Cell · 2016 · 464 citations · Full text

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups

Oscar M. Rueda, Stephen‐John Sammut, José A. Seoane et al. · Nature · 2019 · 419 citations · Full text

Breast Oncology, Medicine, Cancer Recurrence +5