Simon C. C. Lucas

A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification

Paul Bamborough, Chun‐wa Chung, Emmanuel H. Demont et al. · Journal of Medicinal Chemistry · 2019 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Alkene Oxyamination Using Malonoyl Peroxides: Preparation of Pyrrolidines and Isoxazolidines

Carla Alamillo‐Ferrer, Jonathan M. Curle, Stuart C. Davidson et al. · The Journal of Organic Chemistry · 2018 · 25 citations

Natural Sciences, Chemistry, Catalysis +7

Optimization of a Series of 2,3-Dihydrobenzofurans as Highly Potent, Second Bromodomain (BD2)-Selective, Bromo and Extra-Terminal Domain (BET) Inhibitors

Simon C. C. Lucas, Stephen J. Atkinson, Chun‐wa Chung et al. · Journal of Medicinal Chemistry · 2021 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode

Simon C. C. Lucas, Stephen J. Atkinson, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2020 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen

Simon C. C. Lucas, J. Henry Blackwell, Ulf Börjesson et al. · ACS Medicinal Chemistry Letters · 2024 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17