Mark A. West

Validation of Human MDR1-MDCK and BCRP-MDCK Cell Lines to Improve the Prediction of Brain Penetration

Bo Feng, Mark A. West, Nandini C. Patel et al. · Journal of Pharmaceutical Sciences · 2019 · 97 citations

Neuro-oncology, Neuroimaging Biomarkers, Neurophysiology +13

Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: “SLC-Phenotyping” Using Primary Human Hepatocytes

Yi‐An Bi, Chester Costales, Sumathy Mathialagan et al. · Journal of Pharmacology and Experimental Therapeutics · 2019 · 77 citations · Full text

Tumor P-Glycoprotein Correlates with Efficacy of PF-3758309 in in vitro and in vivo Models of Colorectal Cancer

Erica L. Bradshaw‐Pierce, Todd M. Pitts, Aik Choon Tan et al. · Frontiers in Pharmacology · 2013 · 50 citations · Full text

Tumor Xenografts, Chemoprevention Strategy, Tumor P-gp +16

Quantitative prediction of breast cancer resistant protein mediated drug‐drug interactions using physiologically‐based pharmacokinetic modeling

Chester Costales, Jian Lin, Emi Kimoto et al. · CPT Pharmacometrics & Systems Pharmacology · 2021 · 49 citations · Full text

In Vitro–In Vivo Extrapolation of Key Transporter Activity at the Blood–Brain Barrier

Patrick Trapa, Matthew D. Troutman, Thomas Y. K. Lau et al. · Drug Metabolism and Disposition · 2019 · 46 citations · Full text