Leila Rouhi

BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C–deficient mice

Gaëlle Auguste, Leila Rouhi, Scot J. Matkovich et al. · Journal of Clinical Investigation · 2020 · 80 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Haploinsufficiency of<i>Tmem43</i>in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy

Leila Rouhi, Sirisha Cheedipudi, Suet Nee Chen et al. · Cardiovascular Research · 2020 · 51 citations · Full text

Medicine, Genetics, Molecular Genetics +13

Single-Cell RNA Sequencing Uncovers Paracrine Functions of the Epicardial-Derived Cells in Arrhythmogenic Cardiomyopathy

Ping Yuan, Sirisha Cheedipudi, Leila Rouhi et al. · Circulation · 2021 · 50 citations · Full text

Medicine, Cardiology, Genetics +13

The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure

Leila Rouhi, Siyang Fan, Sirisha Cheedipudi et al. · Cardiovascular Research · 2021 · 44 citations · Full text

Life Sciences, Cardiology, Molecular Biology +14

Deletion of the Lmna gene in fibroblasts causes senescence-associated dilated cardiomyopathy by activating the double-stranded DNA damage response and induction of senescence-associated secretory phenotype

Leila Rouhi, Gaëlle Auguste, Qiong Zhou et al. · The Journal of Cardiovascular Aging · 2022 · 33 citations · Full text

Medicine, Cardiology, Genetics +14