Chang Liu

Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial final results

Changsong Qi, Chang Liu, Jifang Gong et al. · Nature Medicine · 2024 · 178 citations

Medicine, Immunology, Oncology +13

Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial

Chang Liu, Zhi Peng, Yanqiao Zhang et al. · The Lancet · 2025 · 105 citations · Full text

Medicine, Oncology, Gastroenterology +8

The AKR1C1–CYP1B1–cAMP signaling axis controls tumorigenicity and ferroptosis susceptibility of extrahepatic cholangiocarcinoma

Chang Liu, Cheng Zhang, Hongkun Wu et al. · Cell Death and Differentiation · 2024 · 20 citations · Full text

Medicine, Molecular Biology, Oncology +17

Phase I study of GUCY2C CAR-T therapy IM96 in patients with metastatic colorectal cancer.

Changsong Qi, Chang Liu, Jian Nan Li et al. · Journal of Clinical Oncology · 2024 · 16 citations

Medicine, Oncology, Pharmacology +11

A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial

Chang Liu, Dan Liu, Yinghua Ji et al. · Nature Medicine · 2025 · 13 citations · Full text

Medicine, Oncology, Pharmacology +17