Lesley McGuffog

Cancer Risks and Mortality in Heterozygous ATM Mutation Carriers

Deborah J. Thompson, Silvia Duedal, Jennifer Kirner et al. · JNCI Journal of the National Cancer Institute · 2005 · 536 citations

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

Karoline Kuchenbaecker, Lesley McGuffog, Daniel Barrowdale et al. · JNCI Journal of the National Cancer Institute · 2016 · 338 citations · Full text

Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms

Miguel de la Hoya, Omar Soukarieh, Irene López‐Perolio et al. · Human Molecular Genetics · 2016 · 89 citations · Full text

A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact

Robert J. MacInnis, Antonis C. Antoniou, Rosalind A. Eeles et al. · Genetic Epidemiology · 2011 · 76 citations · Full text

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

Xianshu Wang, V. Shane Pankratz, Zachary Fredericksen et al. · Human Molecular Genetics · 2010 · 76 citations · Full text