Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers - Concepedia

Concepedia

Publication | Open Access

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

DOI Full Paper Access

338

Citations

30

References

2016

Year

Karoline Kuchenbaecker, Lesley McGuffog, Daniel Barrowdale, Andrew Lee, Penny Soucy, Joe Dennis, Susan M. Domchek, Mark E. Robson, Amanda B. Spurdle, Susan J. Ramus,

JNCI Journal of the National Cancer Institute

Abstract

BC and OC PRS are predictive of cancer risk in BRCA1 and BRCA2 carriers. Incorporation of the PRS into risk prediction models has promise to better inform decisions on cancer risk management.

References

	Year	Citations

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