Brian J. Carroll

Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits

Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli et al. · Journal of Medicinal Chemistry · 1997 · 325 citations · Full text

The Post-Polyketide Synthase Modification Steps in the Biosynthesis of the Antitumor Agent Ansamitocin by <i>Actinosynnema </i><i>p</i><i>retiosum</i>

Peter Spiteller, Linquan Bai, Guangdong Shang et al. · Journal of the American Chemical Society · 2003 · 77 citations

Actinosynnema Pretiosum, Engineering, Aldo-keto Reductase +17

On the Biosynthetic Origin of Methoxymalonyl-Acyl Carrier Protein, the Substrate for Incorporation of “Glycolate” Units into Ansamitocin and Soraphen A

Silke C. Wenzel, Rachel Williamson, Christian Grünanger et al. · Journal of the American Chemical Society · 2006 · 76 citations

Intramolecular proton transfer in the cyclization of geranylgeranyl diphosphate to the taxadiene precursor of taxol catalyzed by recombinant taxadiene synthase

D. Clive Williams, Brian J. Carroll, Qingwu Jin et al. · Chemistry & Biology · 2000 · 75 citations · Full text

Biosynthesis, Intramolecular Proton Transfer, Engineering +11

Identification of a Set of Genes Involved in the Formation of the Substrate for the Incorporation of the Unusual “Glycolate” Chain Extension Unit in Ansamitocin Biosynthesis

Brian J. Carroll, Steven J. Moss, Linquan Bai et al. · Journal of the American Chemical Society · 2002 · 66 citations