Maroof Hasan

TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis

Joschka Willemsen, Marie‐Therese Neuhoff, Thomas Hoyler et al. · Cell Reports · 2021 · 197 citations · Full text

Immunology, Pathology, Cgas/sting-dependent Interferon Responses +18

Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial

Courtney D. DiNardo, Andre C. Schuh, Eytan M. Stein et al. · The Lancet Oncology · 2021 · 185 citations

Phase 1B, Hematological Malignancy, Azacitidine Versus Azacitidine +8

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

Maroof Hasan, James P. Koch, Dinesh Rakheja et al. · Nature Immunology · 2012 · 139 citations · Full text

Molecular Virology, Pathogenesis, Immunology +7

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

Maroof Hasan, Charles S. Fermaintt, Ningguo Gao et al. · Immunity · 2015 · 108 citations · Full text

Medicine, T-regulatory Cell, Immunology +6

Enasidenib vs conventional care in older patients with late-stage mutant-<i>IDH2</i> relapsed/refractory AML: a randomized phase 3 trial

Stéphane de Botton, Pau Montesinos, Andre C. Schuh et al. · Blood · 2022 · 103 citations · Full text

Oral Idh2, Enasidenib Exposure, Mixed-phenotype Acute Leukemia +17