Ming He

Plasticity in designing PROTACs for selective and potent degradation of HDAC6

Wenxing Lv, Ming He, Haiteng Deng et al. · Chemical Communications · 2019 · 105 citations

Life Sciences, Biochemistry, Molecular Biology +13

Centrosome anchoring regulates progenitor properties and cortical formation

Wei Shao, Jiajun Yang, Ming He et al. · Nature · 2020 · 99 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +14

Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

Meixin Li, Yiqing Yang, Qiuye Zhao et al. · Journal of Medicinal Chemistry · 2020 · 62 citations

Life Sciences, Biochemistry, Pharmacology +17

Design, synthesis and biological evaluation of novel dual-acting modulators targeting both estrogen receptor α (ERα) and lysine-specific demethylase 1 (LSD1) for treatment of breast cancer

Ming He, Wentao Ning, Zhiye Hu et al. · European Journal of Medicinal Chemistry · 2020 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Finite element analysis and experimental study on contact pressure of hydraulic support bud-shaped composite sealing ring

Xi Zhang, Gang Wang, Peng Xia et al. · Advances in Mechanical Engineering · 2016 · 21 citations · Full text

Engineering, Materials Engineering, Materials Science +16