Zhiye Hu

Novel Bioactive Hybrid Compound Dual Targeting Estrogen Receptor and Histone Deacetylase for the Treatment of Breast Cancer

Chu Tang, Changhao Li, Silong Zhang et al. · Journal of Medicinal Chemistry · 2015 · 105 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Exploring the PROTAC degron candidates: OBHSA with different side chains as novel selective estrogen receptor degraders (SERDs)

Yuanyuan Li, Silong Zhang, Jing Zhang et al. · European Journal of Medicinal Chemistry · 2019 · 41 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Novel Hybrid Conjugates with Dual Suppression of Estrogenic and Inflammatory Activities Display Significantly Improved Potency against Breast Cancer

Wentao Ning, Zhiye Hu, Chu Tang et al. · Journal of Medicinal Chemistry · 2018 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery of Novel Bicyclic Phenylselenyl-Containing Hybrids: An Orally Bioavailable, Potential, and Multiacting Class of Estrogen Receptor Modulators against Endocrine-Resistant Breast Cancer

Xiangping Deng, Baohua Xie, Qiuzi Li et al. · Journal of Medicinal Chemistry · 2022 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of a Novel Class of PROTACs as Potent and Selective Estrogen Receptor α Degraders to Overcome Endocrine-Resistant Breast Cancer <i>In Vitro</i> and <i>In Vivo</i>

Baohua Xie, Zhinang Yin, Zhiye Hu et al. · Journal of Medicinal Chemistry · 2023 · 31 citations · Full text

Medicine, Oncology, Pharmacology +14