Mika Okamoto

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

Masanori Baba, Osamu Nishimura, Naoyuki Kanzaki et al. · Proceedings of the National Academy of Sciences · 1999 · 755 citations · Full text

Discovery of Novel, Potent, and Selective Small-Molecule CCR5 Antagonists as Anti-HIV-1 Agents:  Synthesis and Biological Evaluation of Anilide Derivatives with a Quaternary Ammonium Moiety

Mitsuru Shiraishi, Yoshio Aramaki, Masaki Seto et al. · Journal of Medicinal Chemistry · 2000 · 185 citations · Full text

Lead Compounds, Cho/ccr5 Cells, Lead Identification +19

Breast Cancer Resistance Protein (BCRP/ABCG2) Induces Cellular Resistance to HIV-1 Nucleoside Reverse Transcriptase Inhibitors

Xin Wang, Tatsuhiko Furukawa, Takao Nitanda et al. · Molecular Pharmacology · 2003 · 139 citations

N-Alkylated Nitrogen-in-the-Ring Sugars: Conformational Basis of Inhibition of Glycosidases and HIV-1 Replication

Naoki Asano, Haruhisa Kizu, Kengo Oseki et al. · Journal of Medicinal Chemistry · 1995 · 134 citations · Full text

Conformational Basis, Combinatorial Chemistry, Bioorganic Chemistry +20

A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1

Ryouji Fujii, Mika Okamoto, Satoko Aratani et al. · Journal of Biological Chemistry · 2001 · 97 citations · Full text