Yuntao Gu

Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration

Jian Chen, Jun-Jun Xie, Mengyun Jin et al. · Cell Death and Disease · 2018 · 135 citations · Full text

Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat

Jian Chen, Jun-Jun Xie, Kesi Shi et al. · Cell Death and Disease · 2018 · 111 citations · Full text

Biomimetic and osteogenic 3D silk fibroin composite scaffolds with nano MgO and mineralized hydroxyapatite for bone regeneration

Ziquan Wu, Zhulong Meng, Qianjin Wu et al. · Journal of Tissue Engineering · 2020 · 93 citations · Full text

Celastrol reduces IL-1β induced matrix catabolism, oxidative stress and inflammation in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration in vivo

Jian Chen, Jun Xuan, Yuntao Gu et al. · Biomedicine & Pharmacotherapy · 2017 · 91 citations

Regenerative Medicine, Inflammation, Degenerative Spine +10

Gastrodin reduces IL-1β-induced apoptosis, inflammation, and matrix catabolism in osteoarthritis chondrocytes and attenuates rat cartilage degeneration in vivo

Jian Chen, Yuntao Gu, Jun-Jun Xie et al. · Biomedicine & Pharmacotherapy · 2017 · 73 citations

Inflammation, Rheumatology, Il-1β-induced Apoptosis +11