Kesi Shi

Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury

Jian Chen, Zhouguang Wang, Zengming Zheng et al. · Cell Death and Disease · 2017 · 173 citations · Full text

A bioactive injectable self-healing anti-inflammatory hydrogel with ultralong extracellular vesicles release synergistically enhances motor functional recovery of spinal cord injury

Chenggui Wang, Min Wang, Kaishun Xia et al. · Bioactive Materials · 2021 · 123 citations · Full text

Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat

Jian Chen, Jun-Jun Xie, Kesi Shi et al. · Cell Death and Disease · 2018 · 111 citations · Full text

A conductive supramolecular hydrogel creates ideal endogenous niches to promote spinal cord injury repair

Biao Yang, Chengzhen Liang, Di Chen et al. · Bioactive Materials · 2021 · 94 citations · Full text

Celastrol reduces IL-1β induced matrix catabolism, oxidative stress and inflammation in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration in vivo

Jian Chen, Jun Xuan, Yuntao Gu et al. · Biomedicine & Pharmacotherapy · 2017 · 91 citations

Regenerative Medicine, Inflammation, Degenerative Spine +10