Jill M. Wetter

Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological Characterization and Broad Preclinical Efficacy in Cognition and Schizophrenia of a Potent and Selective Histamine H3 Receptor Antagonist

Gerard B. Fox, Timothy A. Esbenshade, Jia Bao Pan et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 261 citations

Medicine, Neuroscience, Pharmacology +13

Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain:  Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties

Arthur Gomtsyan, Erol K. Bayburt, Robert G. Schmidt et al. · Journal of Medicinal Chemistry · 2005 · 163 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and Selective Histamine H3 Receptor Antagonist with Drug-Like Properties

Timothy A. Esbenshade, Gerard B. Fox, Kathleen M. Krueger et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 100 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats

Gin C. Hsieh, Prasant Chandran, Anita K. Salyers et al. · Pharmacology Biochemistry and Behavior · 2009 · 82 citations

Medicine, Neuroscience, Pharmacology +16

Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H₄Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models

Marlon Cowart, Robert J. Altenbach, Huaqing Liu et al. · Journal of Medicinal Chemistry · 2008 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16