Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

Roland Schüle, Steven A. Kliewer, Lynn J. Ransone, +4

Cell

Signal TransductionAutoimmune DiseaseG Protein-coupled ReceptorCell SignalingImmunology +6

Identification of a new class of steroid hormone receptors

Vincent Giguère, Na Yang, Prudimar Segui, +1

Nature

MedicineHormonal ReceptorPhysiologyReceptor (Biochemistry)Receptor Biology +4

Retinoic acid is a negative regulator of AP-1-responsive genes.

Roland Schüle, Pundi N. Rangarajan, Na Yang, +5

Proceedings of the National Academy of Sciences

Transcriptional RegulationCell RegulationRetinoic Acid ReceptorMolecular RegulationGenetics +8

Estrogen Inhibits Bone Resorption by Directly Inducing Apoptosis of the Bone-resorbing Osteoclasts

Takashi Kameda, Hiroshi Mano, Tatsuhisa Yuasa, +10

The Journal of Experimental Medicine

Field-Free Isolation of Exosomes from Extracellular Vesicles by Microfluidic Viscoelastic Flows

Chao Liu, Jiayi Guo, Fei Tian, +7

ACS Nano

EngineeringExtracellular MicrovesiclesCytoskeletonOrgan-on-a-chipBiomedical Engineering +18

Identification of an Estrogen Response Element Activated by Metabolites of 17β-Estradiol and Raloxifene

Na Yang, Murali Venugopalan, Sushant Hardikar, +1

Science

Molecular determinants of tissue selectivity in estrogen receptor modulators

Timothy A. Grese, James P. Sluka, Henry U. Bryant, +10

Proceedings of the National Academy of Sciences

Estrogen ReceptorGynecologyRaloxifene AnalogsOvarian CancerMatrix Biology +14

Constitutive Activation of Transcription and Binding of Coactivator by Estrogen-Related Receptors 1 and 2

Wen Xie, Heng Hong, Na Yang, +4

Molecular Endocrinology

Estrogen and raloxifene stimulate transforming growth factor-beta 3 gene expression in rat bone: a potential mechanism for estrogen- or raloxifene-mediated bone maintenance.

Na Yang, H.U. Bryant, Sushant Hardikar, +4

Endocrinology

Developmental BiologyRat BoneHuman GrowthGene ExpressionBone Mineral Density +12

Synthesis and Pharmacology of Conformationally Restricted Raloxifene Analogues:  Highly Potent Selective Estrogen Receptor Modulators

Timothy A. Grese, Lewis D. Pennington, James P. Sluka, +13

Journal of Medicinal Chemistry