Jie Zha

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Huacheng Luo, Ganqian Zhu, Jianfeng Xu et al. · Cancer Cell · 2019 · 212 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2

Bing Xu, Shiyun Wang, Rongwei Li et al. · Cell Death and Disease · 2017 · 143 citations · Full text

Medicine, Oncology, Pharmacology +17

Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition

Jie Zha, Feili Chen, Huijuan Dong et al. · Journal of Translational Medicine · 2014 · 106 citations · Full text

Medicine, Oncology, Pharmacology +15

CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia

Huacheng Luo, Fei Wang, Jie Zha et al. · Blood · 2018 · 90 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair

Jing Ye, Jie Zha, Yuanfei Shi et al. · Clinical Epigenetics · 2019 · 62 citations · Full text

Medicine, Molecular Biology, Oncology +16