Long-acting protein drugs for the treatment of ocular diseases

Joy G. Ghosh, Andrew Nguyen, Chad E. Bigelow, +30

Nature Communications

DNA vaccines expressing glycoprotein complex II antigens gM and gN elicited neutralizing antibodies against multiple human cytomegalovirus (HCMV) isolates

Siyuan Shen, Shixia Wang, William J. Britt, +1

Vaccine

VaccinationVaccine DevelopmentNeutralizing AntibodiesImmunologyGlycoprotein Complex Ii +6

PhoCaL: A Multi-Modal Dataset for Category-Level Object Pose Estimation with Photometrically Challenging Objects

Pengyuan Wang, Hyunjun Jung, Yitong Li, +6

2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)

EngineeringMachine LearningHuman Pose Estimation3D Pose EstimationField Robotics +19

Leonurine attenuates angiotensin II-induced cardiac injury and dysfunction via inhibiting MAPK and NF-κB pathway

Siyuan Shen, Gaojun Wu, Wu Luo, +5

Phytomedicine

High-order differentiable autoencoder for nonlinear model reduction

Siyuan Shen, Yin Yang, Tianjia Shao, +4

ACM Transactions on Graphics

Deep Neural NetworksEngineeringMachine LearningPhysic Aware Machine LearningNonlinear Model Reduction +11

The Discovery of <i>N</i>-(1-Methyl-5-(trifluoromethyl)-1<i>H</i>-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1<i>H</i>-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration

Christopher M. Adams, Karen Anderson, Gerald D. Artman, +32

Journal of Medicinal Chemistry

Ocular DiseaseChoroidal NeovascularizationPharmacotherapyRetinal TherapiesOcular Pharmacology +15

Law Article Prediction Based on Deep Learning

Ge Yan, Yu Li, Siyuan Shen, +2

EngineeringMachine LearningFeature ExtractionJudicial DocumentsWord Segmentation +18

Independent but not synergistic enhancement to the immunogenicity of DNA vaccine expressing HIV-1 gp120 glycoprotein by codon optimization and C3d fusion in a mouse model

Fangjun Liu, Innocent Mboudjeka, Siyuan Shen, +4

Vaccine

VaccinationHuman RetrovirusImmunologyAntiviral ResponseMolecular Biology +7

Deletion of gpUL132, a Structural Component of Human Cytomegalovirus, Results in Impaired Virus Replication in Fibroblasts

Simone Spaderna, Barbara Kropff, Yvonne Ködel, +5

Journal of Virology

Identification of autophagy-related risk signatures for the prognosis, diagnosis, and targeted therapy in cervical cancer

Dan Meng, Hua Jin, Xing Zhang, +8

Cancer Cell International