Juan Castro

Mechanisms of Interferon-alpha induced apoptosis in malignant cells

Lena Thyrell, Sven Erickson, Boris Zhivotovsky et al. · Oncogene · 2002 · 234 citations

Apoptosis, Immunology, Cell Death +6

Molecular mechanisms underlying interferon-α-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins

Olle Sangfelt, Sven Erickson, Juan Castro et al. · Oncogene · 1999 · 140 citations

Transcriptional Regulation, Signal Transduction, Molecular Physiology +12

Induction of apoptosis and inhibition of cell growth are independent responses to interferon-alpha in hematopoietic cell lines.

Olle Sangfelt, Sven Erickson, Juan Castro et al. · PubMed · 1997 · 122 citations

Apoptosis, Immunology, Blood Cell +20

Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence

Sven Erickson, Olle Sangfelt, Mats Heyman et al. · Oncogene · 1998 · 119 citations

T-lymphocyte Senescence, Lymphocyte Development, Immunology +9

Ionizing radiation activates IGF-1R triggering a cytoprotective signaling by interfering with Ku-DNA binding and by modulating Ku86 expression via a p38 kinase-dependent mechanism

Daria Cosaceanu, Raluca A. Budiu, M Carapancea et al. · Oncogene · 2006 · 99 citations

Signal Transduction, Ku-dna Binding, P38 Kinase-dependent Mechanism +11