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Ionizing radiation activates IGF-1R triggering a cytoprotective signaling by interfering with Ku-DNA binding and by modulating Ku86 expression via a p38 kinase-dependent mechanism

Signal TransductionKu-dna BindingP38 Kinase-dependent MechanismCell RegulationRadiation EffectRadiation ExposureKu86 ExpressionCell ProliferationCell BiologyMedicineRadiation OncologyCell SignalingTumor MicroenvironmentHealth Sciences