Tobias W. Fischer

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR‐induced depletion, and protects against the formation of DNA damage (8‐hydroxy‐2'‐deoxyguanosine) in ex vivo human skin

Tobias W. Fischer, Konrad Kleszczyński, Lena H. Hardkop et al. · Journal of Pineal Research · 2012 · 326 citations

Constitutive and UV‐induced metabolism of melatonin in keratinocytes and cell‐free systems

Tobias W. Fischer, Trevor W. Sweatman, Igor Semak et al. · The FASEB Journal · 2006 · 165 citations

Uv Radiation, Melatonin Metabolism, Intracellular Melatonin Metabolism +15

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

Tae‐Kang Kim, Konrad Kleszczyński, Zorica Janjetović et al. · The FASEB Journal · 2013 · 157 citations · Full text

Melatonin enhances mitochondrial <scp>ATP</scp> synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2‐related factor 2 resulting in activation of phase‐2 antioxidant enzymes (<i>γ</i>‐<scp>GCS</scp>,<scp> HO</scp>‐1, <scp>NQO</scp>1) in ultraviolet radiation‐treated normal human epidermal keratinocytes (NHEK)

Konrad Kleszczyński, Detlef Zillikens, Tobias W. Fischer · Journal of Pineal Research · 2016 · 133 citations

Ultraviolet Radiation, Lipid Peroxidation, Atp Synthesis +18

Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp‐9) and effector caspases (casp‐3/casp‐7) and PARP in UVR‐exposed HaCaT keratinocytes

Tobias W. Fischer, Michał A. Żmijewski, Jacobo Wortsman · Journal of Pineal Research · 2007 · 131 citations · Full text