Tobias W. Fischer

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR‐induced depletion, and protects against the formation of DNA damage (8‐hydroxy‐2'‐deoxyguanosine) in ex vivo human skin

Tobias W. Fischer, Konrad Kleszczyński, Lena H. Hardkop et al. · Journal of Pineal Research · 2012 · 332 citations

Life Sciences, Dermatology, Molecular Biology +17

Constitutive and UV‐induced metabolism of melatonin in keratinocytes and cell‐free systems

Tobias W. Fischer, Trevor W. Sweatman, Igor Semak et al. · The FASEB Journal · 2006 · 168 citations

Life Sciences, Biochemistry, Dermatology +12

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

Tae‐Kang Kim, Konrad Kleszczyński, Zorica Janjetović et al. · The FASEB Journal · 2013 · 159 citations · Full text

Life Sciences, Biochemistry, Dermatology +12

Melatonin enhances mitochondrial <scp>ATP</scp> synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2‐related factor 2 resulting in activation of phase‐2 antioxidant enzymes (<i>γ</i>‐<scp>GCS</scp>,<scp> HO</scp>‐1, <scp>NQO</scp>1) in ultraviolet radiation‐treated normal human epidermal keratinocytes (NHEK)

Konrad Kleszczyński, Detlef Zillikens, Tobias W. Fischer · Journal of Pineal Research · 2016 · 137 citations

Life Sciences, Biochemistry, Cell Biology +17

Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp‐9) and effector caspases (casp‐3/casp‐7) and PARP in UVR‐exposed HaCaT keratinocytes

Tobias W. Fischer, Michał A. Żmijewski, Jacobo Wortsman · Journal of Pineal Research · 2007 · 132 citations · Full text

Life Sciences, Cell Biology, Dermatology +17