Konrad Kleszczyński

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR‐induced depletion, and protects against the formation of DNA damage (8‐hydroxy‐2'‐deoxyguanosine) in ex vivo human skin

Tobias W. Fischer, Konrad Kleszczyński, Lena H. Hardkop et al. · Journal of Pineal Research · 2012 · 332 citations

Life Sciences, Dermatology, Molecular Biology +17

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

Tae‐Kang Kim, Konrad Kleszczyński, Zorica Janjetović et al. · The FASEB Journal · 2013 · 159 citations · Full text

Life Sciences, Biochemistry, Dermatology +12

Melatonin enhances mitochondrial <scp>ATP</scp> synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2‐related factor 2 resulting in activation of phase‐2 antioxidant enzymes (<i>γ</i>‐<scp>GCS</scp>,<scp> HO</scp>‐1, <scp>NQO</scp>1) in ultraviolet radiation‐treated normal human epidermal keratinocytes (NHEK)

Konrad Kleszczyński, Detlef Zillikens, Tobias W. Fischer · Journal of Pineal Research · 2016 · 137 citations

Life Sciences, Biochemistry, Cell Biology +17

Metabolism of melatonin in the skin: Why is it important?

Andrzej Słomiński, Igor Semak, Tobias W. Fischer et al. · Experimental Dermatology · 2016 · 122 citations · Full text

Medicine, Biochemistry, Pharmacology +10

Analysis of structure–cytotoxicity in vitro relationship (SAR) for perfluorinated carboxylic acids

Konrad Kleszczyński, Paweł Gardzielewski, Ewa Mulkiewicz et al. · Toxicology in Vitro · 2007 · 98 citations

Pharmacy, Pharmacology, Toxicology +13