Chunlei Wang

Discovery of 6-Fluoro-5-(<i>R</i>)-(3-(<i>S</i>)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4<i>H</i>)-yl)-2-methylphenyl)-2-(<i>S</i>)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1<i>H</i>-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers

Scott H. Watterson, George V. De Lucca, Qing Shi et al. · Journal of Medicinal Chemistry · 2016 · 146 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway

Yuchen Li, Jinju Wang, Shuzhen Chen et al. · Stem Cell Research & Therapy · 2020 · 99 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

miR-143 inhibits glycolysis and depletes stemness of glioblastoma stem-like cells

Shiguang Zhao, Huailei Liu, Yaohua Liu et al. · Cancer Letters · 2013 · 83 citations

Medicine, Molecular Biology, Oncology +14

Tenuigenin Prevents IL-1β-induced Inflammation in Human Osteoarthritis Chondrocytes by Suppressing PI3K/AKT/NF-κB Signaling Pathway

Chunlei Wang, Lihong Zeng, Tao Zhang et al. · Inflammation · 2016 · 79 citations

Life Sciences, Immunology, Orthopedic Surgery +16

PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2's mitochondria translocation

Xu Hou, Yaohua Liu, Huailei Liu et al. · Scientific Reports · 2015 · 78 citations · Full text

Life Sciences, Molecular Biology, Oncology +17