Mark Thomas

A Functional Transsulfuration Pathway in the Brain Links to Glutathione Homeostasis

Victor Vitvitsky, Mark Thomas, Anuja Ghorpade et al. · Journal of Biological Chemistry · 2006 · 235 citations · Full text

2-Anilino-4-(thiazol-5-yl)pyrimidine CDK Inhibitors:  Synthesis, SAR Analysis, X-ray Crystallography, and Biological Activity

Shudong Wang, Christopher Meades, Gavin Wood et al. · Journal of Medicinal Chemistry · 2004 · 151 citations · Full text

X-ray Crystallography, Molecular Docking, Medicinal Chemistry +15

Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line

Anna‐Mart Engelbrecht, Mary Mattheyse, B. Ellis et al. · Cancer Letters · 2007 · 145 citations

Medicine, Induces Apoptosis, Grape Seeds +8

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson’s disease

Mark Thomas, Ashley Reynolds, Victor Vitvitsky et al. · Journal of Neurochemistry · 2006 · 127 citations

Immunology, Reactive Oxygen Species, Social Sciences +19

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure

Wolfgang Döhle, Fabrice Jourdan, Grégory Menchon et al. · Journal of Medicinal Chemistry · 2017 · 127 citations · Full text