Joan Chen

Structure-based Design of Pyridone–Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition

Siegfried Reich, Paul A. Sprengeler, Gary G. Chiang et al. · Journal of Medicinal Chemistry · 2018 · 177 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase

Justin T. Ernst, Peggy A. Thompson, Christian Nilewski et al. · Journal of Medicinal Chemistry · 2020 · 145 citations · Full text

Life Sciences, Oncology, Pharmacology +16

Comparative genomics of microbial drug efflux systems.

Ian T. Paulsen, Joan Chen, Milton H. Saier · PubMed · 2001 · 134 citations

Life Sciences, Genetics, Microbiology +12

High-Throughput Phenotypic Characterization of Pseudomonas aeruginosa Membrane Transport Genes

Daniel Johnson, Sasha G. Tetu, Katherine Phillippy et al. · PLoS Genetics · 2008 · 72 citations · Full text

Life Sciences, Microbiology, Molecular Biology +11

Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A

Peggy A. Thompson, Boreth Eam, Nathan P. Young et al. · Molecular Cancer Therapeutics · 2020 · 45 citations · Full text

Life Sciences, Molecular Biology, Oncology +17