Vertical Transmission of Diverse Microbes in the Tropical Sponge <i>Corticium</i> sp

Koty Sharp, Boreth Eam, D. John Faulkner, +1

Applied and Environmental Microbiology

Structure-based Design of Pyridone–Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition

Siegfried Reich, Paul A. Sprengeler, Gary G. Chiang, +26

Journal of Medicinal Chemistry

Drug TargetMrna TranslationMolecular BiologyCancer BiologyTumor Biology +14

Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase

Justin T. Ernst, Peggy A. Thompson, Christian Nilewski, +20

Journal of Medicinal Chemistry

Direct Interferon-γ Signaling Dramatically Enhances CD4+ and CD8+ T Cell Memory

Jason K. Whitmire, Boreth Eam, Nicola Benning, +1

The Journal of Immunology

Adaptive Immune SystemImmune RegulationImmunologyViral PathogenesisImmunologic Mechanism +17

Tentative T Cells: Memory Cells Are Quick to Respond, but Slow to Divide

Jason K. Whitmire, Boreth Eam, J. Lindsay Whitton

PLoS Pathogens

Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A

Peggy A. Thompson, Boreth Eam, Nathan P. Young, +22

Molecular Cancer Therapeutics

Zotatifin, an eIF4A-Selective Inhibitor, Blocks Tumor Growth in Receptor Tyrosine Kinase Driven Tumors

Adina Gerson‐Gurwitz, Nathan P. Young, Vikas Goel, +10

Frontiers in Oncology

Increasing the CD4+ T Cell Precursor Frequency Leads to Competition for IFN-γ Thereby Degrading Memory Cell Quantity and Quality

Jason K. Whitmire, Nicola Benning, Boreth Eam, +1

The Journal of Immunology

Akt Regulates the Subcellular Localization of the Rab27a‐Binding Protein JFC1 by Phosphorylation

Jennifer L. Johnson, Sandrine Pacquelet, William S. Lane, +2

Traffic

Molecular RegulationSubcellular LocalizationMolecular BiologyJfc1 RedistributionCellular Physiology +18

Mice deficient in stem cell antigen‐1 (Sca1, Ly‐6A/E) develop normal primary and memory CD4⁺ and CD8⁺ T‐cell responses to virus infection

Jason K. Whitmire, Boreth Eam, J. Lindsay Whitton

European Journal of Immunology

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmunologyImmune Regulation +21