Qiang Chen

Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics

Ren‐Bo Ding, Ping Chen, Barani Kumar Rajendran et al. · Nature Communications · 2021 · 91 citations · Full text

Integrative Pharmacogenomics, Subtype-specific Therapeutic Response, Pathology +16

S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy

Jianjie Li, Xiaodong Shu, Jun Xu et al. · Nature Communications · 2022 · 88 citations · Full text

BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis

Qiang Chen, Josh Haipeng Lei, Jiaolin Bao et al. · Advanced Science · 2020 · 87 citations · Full text

Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple‐Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy

Josh Haipeng Lei, Mi‐Hye Lee, Kai Miao et al. · Advanced Science · 2021 · 34 citations · Full text

Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug‐Resistant Model and Genome‐Wide siRNA Screening

Fangyuan Shao, Xueying Lyu, Kai Miao et al. · Advanced Science · 2020 · 22 citations · Full text

Drug Target, Evolution Drug‐resistant Model, Molecular Biology +18