Patient‐Derived Organoids Can Guide Personalized‐Therapies for Patients with Advanced Breast Cancer

Ping Chen, Xu Zhang, Ren‐Bo Ding, +31

Advanced Science

Pdo ModelAdvanced Breast CancerBreast OncologyOncologyDrug Targeting +11

NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation

Kai Miao, Josh Haipeng Lei, Monica Valecha, +19

Nature Communications

Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics

Ren‐Bo Ding, Ping Chen, Barani Kumar Rajendran, +20

Nature Communications

Integrative PharmacogenomicsSubtype-specific Therapeutic ResponsePathologyNasopharyngeal CarcinomaTumor Biology +14

S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy

Jianjie Li, Xiaodong Shu, Jun Xu, +19

Nature Communications

BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis

Qiang Chen, Josh Haipeng Lei, Jiaolin Bao, +9

Advanced Science

Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization

Kun Tan, Lei An, Kai Miao, +17

Proceedings of the National Academy of Sciences

A proteomic atlas of ligand–receptor interactions at the ovine maternal–fetal interface reveals the role of histone lactylation in uterine remodeling

Qianying Yang, Juan Liu, Yue Wang, +15

Journal of Biological Chemistry

Blocking Ubiquitin‐Specific Protease 7 Induces Ferroptosis in Gastric Cancer via Targeting Stearoyl‐CoA Desaturase

Xiaoqing Guan, Yichao Wang, Wen-Kai Yu, +13

Advanced Science

Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination

Yaping Huang, Lin Li, Geng An, +24

Nature Cell Biology

SpermatogenesisGeneticsMolecular GeneticsReproductive BiologyEpigenetics +15

Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLC

Zhen Wu, Zhen Yang, Chun Sun Li, +7

Cancer Medicine