Anthony M.C. Brown

Transformation by Wnt family proteins correlates with regulation of beta-catenin.

Hiroyuki Shimizu, Martin A. Julius, Marianna Giarrè et al. · PubMed · 1997 · 412 citations

Molecular Regulation, Wnt Protein, Cell Proliferation +16

An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/ <i>wingless</i> signaling pathway

Foster C. Gonsalves, Keren Klein, Brittany B. Carson et al. · Proceedings of the National Academy of Sciences · 2011 · 333 citations · Full text

The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.

Roger Bradley, Anthony M.C. Brown · The EMBO Journal · 1990 · 276 citations · Full text

Secreted Protein, Protein Secretion, Signal Transduction +10

Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation.

Louise R. Howe, Osamu Watanabe, James Leonard et al. · PubMed · 2003 · 245 citations

Transcriptional Regulation, Developmental Biology, Twist Expression +15

Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer.

Louise R. Howe, Kotha Subbaramaiah, Jay Patel et al. · PubMed · 2002 · 223 citations

Tumor Biology, Breast Oncology, Endocrine-related Cancer +14