Expression of murine STF-1, a putative insulin gene transcription factor, in β cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny

Yelena Guz, Marc Montminy, Roland Stein, +4

Development

A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release

Zhi‐Liang Chu, Christopher J. Carroll, Jean Alfonso, +11

Endocrinology

Glucose ToleranceSystems BiologySignal TransductionG Protein-coupled ReceptorMedicine +13

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.

James Leonard, Bernard Peers, Ted W. Johnson, +3

Molecular Endocrinology

Somatostatin Gene ExpressionImmunologySomatostatin PromoterPancreas TransplantationInsulin Signaling +20

A Role for β-Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucose-Dependent Insulin Release

Zhi‐Liang Chu, Robert M. Jones, Hongmei He, +13

Endocrinology

Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation.

Louise R. Howe, Osamu Watanabe, James Leonard, +1

PubMed

Transcriptional RegulationDevelopmental BiologyTwist ExpressionSignaling PathwayMedicine +13

Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes.

Helle V. Petersen, Palle Serup, James Leonard, +2

Proceedings of the National Academy of Sciences

GeneticsInsulin SignalingTumor BiologyTranscriptional RegulationSignaling Pathway +16

Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.

Bernard Peers, James Leonard, Surangama Sharma, +2

Molecular Endocrinology

Molecular BiologyPancreas TransplantationInsulin SignalingSignaling PathwayProgressive Restriction +19

Discovery of the First Potent and Orally Efficacious Agonist of the Orphan G-Protein Coupled Receptor 119

Graeme Semple, Beatriz Fioravanti, Imelda Calderon, +16

Journal of Medicinal Chemistry

N-Oleoyldopamine Enhances Glucose Homeostasis through the Activation of GPR119

Zhi‐Liang Chu, Christopher J. Carroll, Ruoping Chen, +12

Molecular Endocrinology

Metabolic SyndromeGlucose ToleranceLipid SynthesisBiochemistryG Protein-coupled Receptor +12

Hormonal Regulation of an Islet-Specific Enhancer in the Pancreatic Homeobox Gene <i>STF-1</i>

Ulupi S. Jhala, Ted W. Johnson, Kevin Ferreri, +2

Molecular and Cellular Biology