Ke Xu

Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro

Ke Xu, Paul J. Thornalley · Biochemical Pharmacology · 2000 · 159 citations

Agriculture, Biochemistry, Toxicology +9

Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro11Abbreviations: BSO, l-buthionine sulphoximine; DNP-SG, S-2,4-dinitrophenylglutathione; DTT, dithiothreitol; GST, glutathione S-transferase; HL60, human leukaemia 60; JNK1, c-Jun N-terminal kinase 1; ML-1, human myeloblastic leukaemia-1; PEITC, phenethyl isothiocyanate; PETC, N-phenethylthiocarbamoyl; PETC-Cys, S-(N-phenethylthiocarbamoyl)cysteine; PETC-SG, S-(N-phenethylthiocarbamoyl)glutathione; and Z-VAD-fmk, N-benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone.

Ke Xu, Paul J. Thornalley · Biochemical Pharmacology · 2001 · 124 citations

Medicine, Cancer Biology, Pharmacology +16

Autophagic secretion of HMGB1 from cancer-associated fibroblasts promotes metastatic potential of non-small cell lung cancer cells via NFκB signaling

Yinghui Ren, Limin Cao, Limin Wang et al. · Cell Death and Disease · 2021 · 111 citations · Full text

Medicine, Cell Biology, Oncology +17

Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells

Xiang Wu, Yu Zhu, Huiqin Yan et al. · BMC Cancer · 2010 · 103 citations · Full text

Medicine, Oncology, Pharmacology +15

Cancer‐associated fibroblasts contribute to cisplatin resistance by modulating <scp>ANXA</scp>3 in lung cancer cells

Limin Wang, Xueqin Li, Yinghui Ren et al. · Cancer Science · 2019 · 98 citations · Full text

Medicine, Cancer Biology, Oncology +14