Xingshu Li

Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer’s Disease Based on the Fusion of Donepezil and Ebselen

Zonghua Luo, Jianfei Sheng, Yang Sun et al. · Journal of Medicinal Chemistry · 2013 · 176 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer’s Disease

Zhiren Wang, Yali Wang, Bo Wang et al. · Journal of Medicinal Chemistry · 2015 · 115 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A novel series of tacrine–selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease

Chuan‐Jun Lu, Qi Zhou, Jun Yan et al. · European Journal of Medicinal Chemistry · 2013 · 98 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors

Ling Huang, Anding Shi, Feng He et al. · Bioorganic & Medicinal Chemistry · 2009 · 93 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation

Wenjun Shan, Ling Huang, Qi Zhou et al. · European Journal of Medicinal Chemistry · 2011 · 87 citations · Full text

Life Sciences, Biochemistry, Pharmacology +12