Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

Siva Sundara Kumar Durairajan, Liang‐Feng Liu, Jiahong Lu, +7

Neurobiology of Aging

Neurodegenerative DiseasesAlzheimer's Diseaseβ-Amyloid PathologyMedicineDegenerative Pathology +5

Design, Synthesis, and Evaluation of Multitarget-Directed Resveratrol Derivatives for the Treatment of Alzheimer’s Disease

Chuan‐Jun Lu, Yueyan Guo, Jun Yan, +5

Journal of Medicinal Chemistry

Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer’s Disease Based on the Fusion of Donepezil and Ebselen

Zonghua Luo, Jianfei Sheng, Yang Sun, +6

Journal of Medicinal Chemistry

Combinatorial ChemistryNeurochemical BiomarkersAlzheimer ’Experimental PharmacologyCholinesterase Inhibitor Donepezil +17

Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo

Jun Yan, Jie Chen, Shun Zhang, +3

Journal of Medicinal Chemistry

Tumor BiologyMedicinal ChemistryDrug TargetingMechanism StudyMedicine +12

Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing <i>Iso</i>combretastatins and Phenstatins as Antitumor Agents

Yanqing Pang, Baijiao An, Lanlan Lou, +5

Journal of Medicinal Chemistry

Multitarget-Directed Benzylideneindanone Derivatives: Anti-β-Amyloid (Aβ) Aggregation, Antioxidant, Metal Chelation, and Monoamine Oxidase B (MAO-B) Inhibition Properties against Alzheimer’s Disease

Ling Huang, Chuan‐Jun Lu, Yang Sun, +6

Journal of Medicinal Chemistry

Fucoxanthin, a Marine Carotenoid, Reverses Scopolamine-Induced Cognitive Impairments in Mice and Inhibits Acetylcholinesterase in Vitro

Jiajia Lin, Ling Huang, Jie Yu, +7

Marine Drugs

Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer’s Disease

Zhiren Wang, Yali Wang, Bo Wang, +3

Journal of Medicinal Chemistry

Design, Synthesis, and Evaluation of Multitarget-Directed Selenium-Containing Clioquinol Derivatives for the Treatment of Alzheimer’s Disease

Zhiren Wang, Yali Wang, Wenrui Li, +4

ACS Chemical Neuroscience

Copper Redox CyclingBioorganic ChemistryLipid PeroxidationNeurochemical BiomarkersAlzheimer ’ +18

A novel series of tacrine–selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease

Chuan‐Jun Lu, Qi Zhou, Jun Yan, +3

European Journal of Medicinal Chemistry

Neurodegenerative DiseasesMedicinal ChemistryAlzheimer's DiseaseNovel SeriesMedicine +8