Van-Loc Nguyen

Identification of 1,5-Naphthyridine Derivatives as a Novel Series of Potent and Selective TGF-β Type I Receptor Inhibitors

Françoise Gellibert, James M. Woolven, Marie-Hélène Fouchet et al. · Journal of Medicinal Chemistry · 2004 · 222 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Substituted 2-[(4-Aminomethyl)phenoxy]-2-methylpropionic Acid PPARα Agonists. 1. Discovery of a Novel Series of Potent HDLc Raising Agents

Michael L. Sierra, Véronique Bénéton, Anne-Bénédict Boullay et al. · Journal of Medicinal Chemistry · 2007 · 120 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151

Olivier Mirguet, Yann Lamotte, Frédéric Donche et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 118 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +6

Discovery of 4-{4-[3-(Pyridin-2-yl)-1<i>H</i>-pyrazol-4-yl]pyridin-2-yl}-<i>N</i>-(tetrahydro-2<i>H</i>- pyran-4-yl)benzamide (GW788388):  A Potent, Selective, and Orally Active Transforming Growth Factor-β Type I Receptor Inhibitor

Françoise Gellibert, Anne‐Charlotte de Gouville, James M. Woolven et al. · Journal of Medicinal Chemistry · 2006 · 103 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15