PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

Junwei Hou, Rongce Zhao, Weiya Xia, +20

Nature Cell Biology

Tumor BiologyMedicineApoptosisImmunologyPharmacology +11

Hesperidin Is a Potential Inhibitor against SARS-CoV-2 Infection

Fang‐Ju Cheng, Thanh-Kieu Huynh, Chia‐Shin Yang, +8

Nutrients

Common FlavanoneMedicineImmunologyViral PathogenesisAntiviral Drug Development +11

K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression

Han‐Tsang Wu, Yi-Chih Kuo, Jung‐Jyh Hung, +9

Nature Communications

Tannic acid suppresses SARS-CoV-2 as a dual inhibitor of the viral main protease and the cellular TMPRSS2 protease

Shao‐Chun Wang, Yeh Chen, Yuchuan Wang, +7

PubMed Central

Fur regulation of the capsular polysaccharide biosynthesis and iron-acquisition systems in Klebsiella pneumoniae CG43

Ching‐Ting Lin, Chien-Chen Wu, Yusheng Chen, +5

Microbiology

Purification and characterization of an aspartic protease from the Rhizopus oryzae protease extract, Peptidase R

Nai‐Wan Hsiao, Yeh Chen, Yi-Chia Kuan, +4

Electronic Journal of Biotechnology

Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug.

Yuchuan Wang, Wenhao Yang, Chia‐Shin Yang, +5

PubMed

Osthole Inhibits Insulin-like Growth Factor-1-Induced Epithelial to Mesenchymal Transition via the Inhibition of PI3K/Akt Signaling Pathway in Human Brain Cancer Cells

Ying-Chao Lin, Jia-Ching Lin, Chao-Ming Hung, +6

Journal of Agricultural and Food Chemistry

PathologyPi3k/akt Signaling PathwayCancer BiologyGliomaTumor Biology +18

MLL3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway

Han‐Tsang Wu, Yi-En Liu, Kai‐Wen Hsu, +4

The American Journal of Chinese Medicine

Breast OncologyMedicineApoptosisMll3 InducedEstrogen Receptor +13

BiTE‐Secreting CAR‐<i>γδ</i>T as a Dual Targeting Strategy for the Treatment of Solid Tumors

Shi‐Wei Huang, Chih‐Ming Pan, Yu‐Chuan Lin, +15

Advanced Science