Chaohua Zhang

Targeted Inhibition of the Molecular Chaperone Hsp90 Overcomes ALK Inhibitor Resistance in Non–Small Cell Lung Cancer

Jim Sang, Jaime Acquaviva, Julie C. Friedland et al. · Cancer Discovery · 2013 · 210 citations

Medicine, Oncology, Pharmacology +17

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair

Ming Tang, Zhiming Li, Chaohua Zhang et al. · Science Advances · 2019 · 145 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Overcoming Acquired BRAF Inhibitor Resistance in Melanoma via Targeted Inhibition of Hsp90 with Ganetespib

Jaime Acquaviva, Donald L. Smith, John-Paul Jimenez et al. · Molecular Cancer Therapeutics · 2014 · 102 citations

Medicine, Oncology, Pharmacology +14

Targeting KRAS-Mutant Non–Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib

Jaime Acquaviva, Donald L. Smith, Jim Sang et al. · Molecular Cancer Therapeutics · 2012 · 98 citations

Medicine, Oncology, Pharmacology +14

Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models

David A. Proia, Jim Sang, Suqin He et al. · Investigational New Drugs · 2012 · 80 citations · Full text

Medicine, Oncology, Pharmacology +14