John-Paul Jimenez

Targeted Inhibition of the Molecular Chaperone Hsp90 Overcomes ALK Inhibitor Resistance in Non–Small Cell Lung Cancer

Jim Sang, Jaime Acquaviva, Julie C. Friedland et al. · Cancer Discovery · 2013 · 210 citations

Medicine, Oncology, Pharmacology +17

Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in <i>In Vitro</i> and <i>In Vivo</i> Models of Non–Small Cell Lung Cancer

Takeshi Shimamura, Samanthi A. Perera, Kevin P. Foley et al. · Clinical Cancer Research · 2012 · 166 citations

Medicine, Oncology, Pharmacology +13

Overcoming Acquired BRAF Inhibitor Resistance in Melanoma via Targeted Inhibition of Hsp90 with Ganetespib

Jaime Acquaviva, Donald L. Smith, John-Paul Jimenez et al. · Molecular Cancer Therapeutics · 2014 · 102 citations

Medicine, Oncology, Pharmacology +14

FGFR3 Translocations in Bladder Cancer: Differential Sensitivity to HSP90 Inhibition Based on Drug Metabolism

Jaime Acquaviva, Suqin He, Chaohua Zhang et al. · Molecular Cancer Research · 2014 · 76 citations

Medicine, Oncology, Pharmacology +16

Preclinical Activity Profile and Therapeutic Efficacy of the HSP90 Inhibitor Ganetespib in Triple-Negative Breast Cancer

David A. Proia, Chaohua Zhang, Manuel Sequeira et al. · Clinical Cancer Research · 2013 · 63 citations

Medicine, Oncology, Pharmacology +17