Vijay K. Chaudhary

A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin

Vijay K. Chaudhary, Gary Queen, Richard P. Junghans et al. · Nature · 1989 · 418 citations

Life Sciences, Immunology, Microbiology +13

Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity.

Vijay K. Chaudhary, Yoshihiro Jinno, David FitzGerald et al. · Proceedings of the National Academy of Sciences · 1990 · 264 citations

Life Sciences, Biochemistry, Molecular Biology +14

Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein

Vijay K. Chaudhary, Tamio Mizukami, Thomas R. Fuerst et al. · Nature · 1988 · 254 citations

Life Sciences, Immunology, Microbiology +11

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol

M Ogata, Vijay K. Chaudhary, Ira Pastan et al. · Journal of Biological Chemistry · 1990 · 231 citations · Full text

Life Sciences, Biochemistry, Microbiology +15

Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL.

Saraswathy Seetharam, Vijay K. Chaudhary, David Fitzgerald et al. · Journal of Biological Chemistry · 1991 · 215 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14