Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells

Yu J. Shen, Nina Le Bert, Anuja Chitre, +7

Cell Reports

Lymphoid NeoplasiaGenome InstabilityImmunologyImmunologic MechanismCytosolic Nucleotides +7

RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma

Adeline R. Lam, Nina Le Bert, Samantha S.W. Ho, +9

Cancer Research

ImmunologyNk CellsImmunoeditingRae1 LigandsImmunotherapy +14

Blocking IFNAR1 inhibits multiple myeloma–driven Treg expansion and immunosuppression

Yawara Kawano, Oksana Zavidij, Jihye Park, +24

Journal of Clinical Investigation

T-regulatory CellImmunologyImmune RegulationRegulatory T CellsImmunologic Mechanism +14

Expression of ERCC1 antisense RNA abrogates gemicitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair.

Li Ying Yang, Lan Li, Hong Jiang, +2

PubMed

Tumor BiologyGenome InstabilityCddp-dna AdductsMedicinePathology +12

Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma

Salomon Manier, Daisy Huynh, Yu J. Shen, +19

Science Translational Medicine

Microbial fuel-cell-based toxicity sensor for fast monitoring of acidic toxicity

Yu J. Shen, Olivier Lefebvre, Zi Tan, +1

Water Science & Technology

EngineeringMicrobial Electrochemical SystemBioelectrochemical ReactorBiofuel CellWastewater Treatment +18

Progression signature underlies clonal evolution and dissemination of multiple myeloma

Yu J. Shen, Yuji Mishima, Jiantao Shi, +16

Blood

RNA Polymerase III Regulates Cytosolic RNA:DNA Hybrids and Intracellular MicroRNA Expression

Christine X. Koo, Kouji Kobiyama, Yu J. Shen, +6

Journal of Biological Chemistry

STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression

Nina Le Bert, Adeline R. Lam, Samantha S.W. Ho, +3

OncoImmunology

Cross-species transcriptomic signatures identify mechanisms related to species sensitivity and common responses to nanomaterials

Becky J. Curtis, Nicholas J. Niemuth, Evan A. Bennett, +8

Nature Nanotechnology

BiologyBioinformaticsEngineeringBiomolecular ToolNanobiotechnology +11