AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate

Qilin Gu, Xiaojie Yang, Jie Lv, +19

Science

HyperlipidemiaAibp-mediated Cholesterol EffluxHematologyStem CellsAtherosclerosis +16

OX40 Costimulation Inhibits Foxp3 Expression and Treg Induction via BATF3-Dependent and Independent Mechanisms

Xiaolong Zhang, Xiang Xiao, Peixiang Lan, +8

Cell Reports

A Zebrafish Thrombosis Model for Assessing Antithrombotic Drugs

Xiaoyu Zhu, Hong‐Cui Liu, Shengya Guo, +5

Zebrafish

PharmacotherapyPre-clinical PharmacologyDrug ResistanceZebrafish ThrombosisThrombosis +15

BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

Sen Zhu, Dongyu Zhao, Yan Lin, +16

Nature Communications

A Zebrafish Heart Failure Model for Assessing Therapeutic Agents

Xiaoyu Zhu, Siqi Wu, Shengya Guo, +4

Zebrafish

Heart FailureCardiovascular PharmacologyCardiac RegenerationPharmacotherapyCardiovascular Function +18

Fenobucarb-induced developmental neurotoxicity and mechanisms in zebrafish

Xiaoyu Zhu, Yuying Wu, Bo Xia, +5

NeuroToxicology

Fenobucarb-induced Developmental NeurotoxicityMedicineNeurogenesisNeuroprotectionNeuroscience +3

Machine learning uncovers cell identity regulator by histone code

Bo Xia, Dongyu Zhao, Guangyu Wang, +10

Nature Communications

Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks

Yang Yu, Nhung Pham, Bo Xia, +6

Nature

ChromatinGenome InstabilityDna DamageChromatin RemodelingGenetics +7

Epigenetic landscape reveals MECOM as an endothelial lineage regulator

Jie Lv, Shu Meng, Qilin Gu, +17

Nature Communications

Epigenetic ChangeCardiac RegenerationEndothelial Cell LineageEpigeneticsAngiogenesis +18

Low RNA stability signifies increased post-transcriptional regulation of cell identity genes

Yanqiang Li, Yi Yang, Jie Lv, +12

Nucleic Acids Research

Histone ModificationsEngineeringEpigenetic ChangeGeneticsRna Decay +18