Paul W. Smith

Inhibition of HIV replication by amino‐sugar derivatives

George W. J. Fleet, Abraham Karpas, Raymond A. Dwek et al. · FEBS Letters · 1988 · 348 citations · Full text

Potent competitive inhibition of α-galactosidase and α-glucosidase activity by 1,4-dideoxy-1,4-iminopentitols: syntheses of 1,4-dideoxy-1,4-imino-d-lyxitol and of both enantiomers of 1,4-dideoxy-1,4-iminoarabinitol

George W. J. Fleet, S. J. NICHOLAS, Paul W. Smith et al. · Tetrahedron Letters · 1985 · 222 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +5

Enantiospecific syntheses of deoxymannojirimycin, fagomine and 2r,5r-dihydroxymethyl-3r,4r-dihydroxypyrrolidine from D-glucose

George W. J. Fleet, Paul W. Smith · Tetrahedron Letters · 1985 · 115 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +4

Synthesis of deoxymannojirimycin fagomine deoxynojirimycin 2-acetamido-1,5-imino-1,2,5-trideoxy-D-mannitol 2-acetamido-1,5-imino-1,2,5-trideoxy-D-glucitol 2S,3R,4R,5R-trihydroxypipecolic acid and 2S,3R,4R,5S-trihydroxypipecolic acid from methyl 3-O-benzyl-2,6-dideoxy-2,6-imino-α-D-mannofuranoside

George W. J. Fleet, Linda E. Fellows, Paul W. Smith · Tetrahedron · 1987 · 104 citations

Diversity Oriented Synthesis, Bioorganic Chemistry, Biochemistry +9

Synthesis of the α-Mannosidase inhibitors swainsonine [(1S, 2R, 8R, 8aR)-1,2,8-trihydroxyoctahydroindolizine] and 1,4-dideoxy-1,4-imino-d-mannitol from mannose

Bharat P. Bashyal, George W. J. Fleet, M. J. GOUGH et al. · Tetrahedron · 1987 · 91 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +9