Cytochrome <i>c</i> Oxidase Is Required for the Assembly/Stability of Respiratory Complex I in Mouse Fibroblasts

Francisca Díaz, Hirokazu Fukui, Sofía García, +1

Molecular and Cellular Biology

Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency

Francisca Díaz, Christine K. Thomas, Sofía García, +2

Human Molecular Genetics

A defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions

Francisca Díaz, Sofía García, Kyle R. Padgett, +1

Human Molecular Genetics

Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease

Sandra R. Bacman, Siôn L. Williams, Sofía García, +1

Gene Therapy

Organ-specific ShiftsMitochondrial BiogenesisMitochondrial FunctionMitochondrial DynamicNatural Sciences +8

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels

Susana Peralta, Steffi Goffart, Siôn L. Williams, +6

Journal of Cell Science

ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly

Tania Arguello, Susana Peralta, Hana Antonická, +7

Cell Reports

Overexpression of <scp>PGC</scp>‐1α in aging muscle enhances a subset of young‐like molecular patterns

Sofía García, Nadee Nissanka, Edson Assunção Mareco, +6

Aging Cell

Muscle FunctionAgingBiogerontologyCellular PhysiologyMuscle Physiology +15

Pathophysiology and fate of hepatocytes in a mouse model of mitochondrial hepatopathies

Francisco J. Díaz, Sofía García, D Hernandez, +4

Gut

Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse

Lloye M. Dillon, Aline Hida, Sofía García, +2

PLoS ONE

AgingMitochondrial DysfunctionGeneticsImmunologySpleen Phenotypes +26

Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage

Susana Peralta, Alessandra Torraco, Tina Wenz, +3

Human Molecular Genetics

Conditional Ndufa5 KnockoutGeneticsNeurochemical BiomarkersSynaptic SignalingCns Conditional Ablation +25