Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells11Abbreviations: EPO, erythropoietin; VEGF, vascular endothelial growth factor; HIF, hypoxia-inducible factor; NO, nitric oxide; NOS, nitric oxide synthase; CO, carbon monoxide; sGC, soluble guanylate cyclase; cGMP, cyclic GMP; YC-1, 3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole; SNP, sodium nitroprusside; ODQ, 1H-(1,2,4)oxadiazole (4,3a)quinoxatin-1-one; MB, methylene blue; NAME, N(G)-nitro-L-arginine methyl ester; RT-PCR, reverse transcription polymerase chain reaction; and EMSA, electrophoretic mobility gel shift.

Yang-Sook Chun, Eun-Jin Yeo, Eunjoo Choi, +4

Biochemical Pharmacology

Dna2 of Saccharomyces cerevisiae Possesses a Single-stranded DNA-specific Endonuclease Activity That Is Able to Act on Double-stranded DNA in the Presence of ATP

Sung-Ho Bae, Eunjoo Choi, Kyoung Hwa Lee, +3

Journal of Biological Chemistry

Hypoxic activation of the atrial natriuretic peptide gene promoter through direct and indirect actions of hypoxia-inducible factor-1

Yang‐Sook Chun, Ju-Yeon HYUN, Yong‐Geun Kwak, +5

Biochemical Journal

Genetic Analyses of<i>Schizosaccharomyces pombe dna2</i>+ Reveal That Dna2 Plays an Essential Role in Okazaki Fragment Metabolism

Hoyoung Kang, Eunjoo Choi, Sung-Ho Bae, +6

Genetics

GeneticsMolecular BiologyMolecular GeneticsCell CycleOkazaki Fragment Metabolism +14

A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses

Yang‐Sook Chun, Eunjoo Choi, Eun-Jin Yeo, +3

Journal of Cell Science

Cadmium blocks hypoxia‐inducible factor (HIF)‐1‐mediated response to hypoxia by stimulating the proteasome‐dependent degradation of HIF‐1α

Yang‐Sook Chun, Eunjoo Choi, Gi‐Tae Kim, +5

European Journal of Biochemistry

Proteasome‐dependent DegradationImmunologyRedox BiologyOxidative StressTranscriptional Regulation +16

A dominant-negative isoform lacking exons 11 and 12 of the human hypoxia-inducible factor-1α gene

Yang‐Sook Chun, Eunjoo Choi, Tae‐You Kim, +2

Biochemical Journal

Dominant-negative IsoformGeneticsRedox BiologyCellular PhysiologyOxidative Stress +15

Zinc Induces the Accumulation of Hypoxia-Inducible Factor (HIF)-1α, but Inhibits the Nuclear Translocation of HIF-1β, Causing HIF-1 Inactivation

Yang-Sook Chun, Eunjoo Choi, Gi‐Tae Kim, +5

Biochemical and Biophysical Research Communications

Hypoxia-inducible FactorCausing Hif-1 InactivationRedox RegulatorPhysiologyHypoxia (Medicine) +7

Phorbol ester stimulates the nonhypoxic induction of a novel hypoxia-inducible factor 1alpha isoform: implications for tumor promotion.

Yang Sook Chun, Kyoung Hwa Lee, Eunjoo Choi, +5

PubMed

Cancer BiologyTumor BiologyOxidative StressRedox RegulatorCancer Cell Biology +16

A dominant-negative isoform lacking exons 11 and 12 of the human hypoxia-inducible factor-1α gene

Yang‐Sook Chun, Eunjoo Choi, Tae-You KIM, +2

Biochemical Journal

Dominant-negative IsoformGeneticsRedox BiologyCellular PhysiologyOxidative Stress +18