CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

Yoko Kojima, Jens-Peter Volkmer, Kelly M. McKenna, +15

Nature

ImmunologyAutoimmunityImmunotherapyMedicineCd47-blocking Antibodies +1

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

Jongmin Kim, Yujung Kang, Yoko Kojima, +9

Nature Medicine

HypertensionPulmonary Arterial HypertensionAngiogenesisCardiovascular DiseasePhysiology +8

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

Hyung J. Chun, Ziad A. Ali, Yoko Kojima, +12

Journal of Clinical Investigation

MicroRNA‐26a is a novel regulator of vascular smooth muscle cell function

Nicholas J. Leeper, Azad Raiesdana, Yoko Kojima, +7

Journal of Cellular Physiology

Cardiac RegenerationCellular PhysiologyTranscriptional RegulationAbdominal Aortic AneurysmSmc Differentiation +18

The Role of Efferocytosis in Atherosclerosis

Yoko Kojima, Irving L. Weissman, Nicholas J. Leeper

Circulation

Necrotic CoreVascular DiseasePlaque ProgressionApoptosisImmunology +19

Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis

Alyssa M. Flores, Niloufar Hosseini-Nassab, Kai-Uwe Jarr, +15

Nature Nanotechnology

NanoparticlesInflammationPro-efferocytic NanoparticlesEngineeringTherapeutic Nanomaterials +9

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

Paola Betancur, Brian J. Abraham, Ying Ying Yiu, +15

Nature Communications

Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

Nicholas J. Leeper, Maureen M. Tedesco, Yoko Kojima, +6

American Journal of Physiology-Heart and Circulatory Physiology

ImmunologyImmune RegulationCell DeathRenal InflammationInflammation +16

Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis

Yoko Kojima, Kelly Downing, Ramendra Kundu, +9

Journal of Clinical Investigation

InflammationVascular DiseaseSignal TransductionChromosome 9P21Cardiovascular Disease +10

Endothelial Lipase Modulates Susceptibility to Atherosclerosis in Apolipoprotein-E-deficient Mice

Tatsuro Ishida, Sungshin Choi, Ramendra K. Kundu, +6

Journal of Biological Chemistry

Vascular DiseaseImmunologyHyperlipidemiaOxidative StressInflammation +14